The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Turmeric (curcumin) improves postoperative pain and fatigue

    Researchers at Vardhman Mahavir Medical College and Safdarjung Hospital, in New Delhi, India, studied the effect of curcumin on pain and fatigue following laparoscopic cholecystectomy (gallbladder surgery).

    First, the details.

    • 50 consecutive patients scheduled for laparoscopic cholecystectomy received general anesthesia and an analgesia protocol.
      • Curcumin
      • Placebo
    • Analgesics were taken if the assigned treatments provided insufficient pain relief.
    • Patients maintained pain/fatigue/adverse event diaries based on 100-point pain scale and 10-point fatigue scale.
    • Pain and fatigue levels at day 3 and weeks 1,2 and 3 were evaluated.

    And, the results.

    • Pain and fatigue scores at day 3 were similar in the 2 groups.
    • At weeks 1 and 2, the curcumin group showed significantly lower average pain scores — 15 vs 30 for placebo.
    • Fatigue scores at weeks 1, 2, and 3 were significantly lower in the curcumin group — 2, 1, and 0, respectively, vs 5, 4, and 1 for placebo.
    • All patients were pain free at week 3.
    • The use of pain medicine was significantly lower in the curcumin group — 7 vs 4 for placebo.

    The bottom line?

    A PubMed search shows this as the first study of patients treated for pain following gallbladder surgery.

    6/28/11 21:44 JR

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