The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    If you found the information here helpful, please consider supporting this site.If you found the information here helpful, please consider supporting this site.

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    St John’s wort and hot flushes in women with breast cancer history

    There are few effective treatments for hot flushes in post-menopausal breast cancer survivors.

    During the annual meeting of the American Society of Clinical Oncology, researchers at Wake Forest University School of Medicine, in Winston-Salem, North Carolina reported the results from a pilot study.

    First, the details.

    • 9 women at least 2 years after active treatment for non-metastatic breast cancer, and with a minimum of 3 hot flushes per day or 21 per week participated.
    • Women were ineligible if they were being treated for hot flushes (eg, estrogen, antidepressants).
    • Participants took 3, 300 mg St. John’s wort capsules daily for 4 weeks.
    • Participants completed hot flush diaries during active treatment (weeks 1-4), and for 2 weeks post-treatment (weeks 5-6) to assess hot flush frequency and severity.
    • In addition, women completed quality of life assessments.

    And, the results.

    • St. John’s Wort was not effective in reducing the frequency or severity of hot flushes.
    • Quality of life was not improved.
    • No adverse events were reported.

    The bottom line?

    The authors concluded, “St. John’s Wort was not effective.”

    Others also reported a lack of effect.

    6/6/11 20:20 JR

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