The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Safety of vitamin D during pregnancy

    Researchers at the Medical University of South Carolina in Charleston, studied healthy expectant mothers.

    First, the details.

    • 494 women at 12-16 weeks’ gestation received 400, 2000 or 4000 IU vitamin D(3) /day until delivery.
    • Maternal and neonatal circulating 25(OH)D at delivery were measured.

    And, the results.

    • The average blood levels of 25(OH)D at delivery and 1-month before delivery were significantly different among the groups.
    • The percent that achieved sufficient levels was significantly different by group — greatest in 4000 IU group.
    • Circulating levels of 25(OH)D had a significant and direct influence on circulating 1,25(OH)(2) D concentrations throughout pregnancy.
    • There were no differences between groups on any safety measure.
    • No side effects attributed to vitamin D supplementation or circulating 25(OH)D levels were reported.

    The bottom line?

    The authors concluded, “Vitamin D supplementation of 4,000 IU/day for pregnant women was safe and most effective in achieving sufficiency in all women and their neonates regardless of race.”

    More on this study is summarized here.

    6/28/11 22:29 JR

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