The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    If you found the information here helpful, please consider supporting this site.If you found the information here helpful, please consider supporting this site.

  • Recent Posts

  • Recent Comments

    Review: EPA to treat depression

    Researchers at the New York State Psychiatric Institute, in New York City, used a meta-analysis to test the hypothesis that eicosapentaenoic acid (EPA) is the effective component in omega-3 fatty acid treatment of major depressive episodes.

    First, the details.

    • 15 studies involving 916 participants were included.
    • A depressive episode was the primary complaint (with or without comorbid medical conditions).

    And, the results.

    • Supplements containing at least 60% EPA showed significant benefit on depression scores vs supplements with less than 60% EPA.
      • Treatment duration or patient age did not affect the results.
    • Supplements with EPA less than 60% were ineffective.
    • Improvement was associated with a dose of EPA that was greater than docosahexaenoic acid (DHA), within the range of 200 to 2,200 mg/day of EPA.

    The bottom line?

    The authors concluded, “Supplements containing EPA at least 60% of total EPA + DHA, in a dose range of 200 to 2,200 mg/d of EPA in excess of DHA, were effective against primary depression.

    So, now you have guidelines for selecting an omega-3 supplement.

    10/27/11 20:18 JR

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