The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Vitamins C, D, and mood disturbance in hospitalized patients

    Low blood levels of vitamins C and D are prevalent in acutely hospitalized patients.

    Researchers at McGill University, and Jewish General Hospital, in Montreal, Quebec, looked for a change in mood after raising blood levels of these vitamins.

    First, the details.

    • 55 patients were assigned to a treatment group.
      • Vitamin C 500 mg twice daily
      • Vitamin D 1000 IU twice daily
    • Changes in mood were assessed using the Profile of Mood States.
    • Neither the patients nor researchers knew the treatment given — double blind.

    And, the results.

    • 32 patients completed the study.
    • Vitamin C therapy significantly increased vitamin C levels in blood.
      • This was associated with a significant 34% reduction in mood disturbance.
    • Vitamin D therapy significantly increased 25-hydroxyvitamin D blood concentrations.
      • But this was not accompanied by a significant effect on mood.

    The bottom line?

    Despite the absence of a placebo control group, the authors concluded, “Treatment of hypovitaminosis C improves the mood state of acutely hospitalized patients.”

    10/8/10 20:21 JR

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