The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Tai chi for depression in elderly patients taking Lexapro

    Nearly two-thirds of elderly patients treated for depression fail to achieve symptomatic remission and functional recovery with first-line pharmacotherapy.

    Researchers at the University of California, Los Angeles, studied whether a mind-body exercise, tai chi, added to escitalopram (Lexapro) might augment the treatment of geriatric depression.

    First, the details.

    • 112 older adults with major depression were treated with escitalopram for approximately 4 weeks.
    • 73 partial responders to escitalopram continued to receive escitalopram daily and were randomly assigned to 2 hours per week of an adjunct treatment for 10 weeks.
      • Tai chi
      • Health education
    • All participants underwent evaluation of depression, anxiety, resilience, health-related quality of life, cognition, and inflammation during 14 weeks of follow-up.

    And, the results.

    • Those treated with escitalopram + tai chi were more likely to show a greater reduction in depressive symptoms and remission vs those receiving escitalopram + health education.
    • Those in the escitalopram + tai chi group also showed significantly greater improvements in 36-Item Short Form Health Survey physical functioning and cognitive tests and a decline in the inflammatory marker, C-reactive protein, vs the escitalopram + health education group.

    The bottom line?

    The authors concluded, “Complementary use of a mind-body exercise, such as tai chi, may provide additional improvements of clinical outcomes in the pharmacologic treatment of geriatric depression.”

    On it’s own, tai chi reduces symptoms of depression. It would have been interesting to see how well the partial responders responded to tai chi alone.

    3/6/11 17:25 JR

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