The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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  • Recent Comments

    Preventing recurrent bacterial vaginosis with probiotics, conveniently

    Researchers at Shanghai Jiao Tong University School of Medicine, in China report positive results with a simplified probiotic treatment regimen.

    First, the details.

    • 120 healthy Chinese women with a history of recurrent bacterial vaginosis were randomly assigned to a treatment group for 7 days of treatment, then 7 days of no treatment, and 7 days of treatment again.
      • Vaginal prophylaxis with 1 capsule (Probaclac Vaginal; Nicar Laboratories) containing 8 billion colony-forming units of Lactobacillus rhamnosus, L acidophilus, and Streptococcus thermophilus
      • Placebo capsule
    • Bacterial vaginosis is the most common vaginal infection, with symptoms that include an odorous vaginal discharge.

    And, the results.

    • Probiotic preventive treatment (prophylaxis) resulted in significantly lower recurrence rates for bacterial vaginosis (16% vs 45%) and Gardnerella vaginalis incidence through 2 months (4% vs 18%).
      • Gardnerella vaginalis is an infection of the female genital tract.
    • Between the 2- and 11-month follow-up periods, women who received probiotics reported a lower incidence of bacterial vaginosis and G. vaginalis.
    • No side effects were reported in either study group.

    The bottom line?

    Aside from the effectiveness of the probiotic treatment, most interesting is that long-term prevention (11 months) required a short period of treatment — 2, 7 day treatments separated by 7 days off treatment.

    Earlier this year, researchers in Italy reported the effectiveness of a long-term (24 months) intravaginal treatment with Lactobacillus rhamnosus (Normogin) on vaginal symptoms in 40 women with bacterial vaginosis.

    There’s a need for convenient preventive therapy. Researchers in Belgium, in a review of the treatment of bacterial vaginosis concluded, “Treatment remains cumbersome and clinicians are currently rather poorly armed to treat bacterial vaginosis in the long run.”

    9/13/10 21:54 JR

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