The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Omega-3 and advanced prostate cancer

    Researchers from the University of California, San Francisco report that omega-3 protects against advanced prostate coancer.

    And there’s a COX-2 genetic connection.

    First, the details.

    • 466 men with aggressive prostate cancer were compared to 478 age- and ethnicity-matched controls.
    • Diet was assessed using a food frequency questionnaire.
    • DNA was assessed to identify a COX-2 genetic connection.

    And, the results.

    • Increasing intake of omega-3 fatty acids was significantly associated with a decreased risk of aggressive prostate cancer.
    • The protective effect was even stronger in men who carried the COX-2 rs4647310 gene — a risk factor for prostate cancer.

    The bottom line?
    The authors concluded, “Dietary long chain omega-3 polyunsaturated fatty acids appear protective for aggressive prostate cancer.”

    In addition, the increased risk of prostate cancer associated with the COX-2 rs4647310 gene was “essentially reversed by increasing omega-3 fatty acid intake by a half a gram per day,” Dr. John Witte said in a Medscape interview.

    A recent review nutrition and prostate cancer concurs regarding the benefits of omega-3 as it relates to prostate cancer risk. Now, we have data on the risk of advanced prostate cancer.

    3/27/09 20:01 JR

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