The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Associations between cannabis and psychosis

    Writing on Medscape, Dr. Michael Compton reviewed the effects of marijuana.

    Here’s what we know.

    • It’s the most abused illicit substance in the US, and the most abused illegal drug among people with schizophrenia.
      • Furthermore, the initiation of cannabis use among those with psychotic disorders often precedes the onset of psychosis by several years.
    • Cannabis use in adolescence is an independent risk factor for psychosis and schizophrenia.
      • Cannabis use may interact with genetic factors to elevate risk for psychotic disorders.
    • Preliminary research suggests that cannabis use before the manifestation of psychiatric symptoms may be associated with an earlier age at onset of psychotic symptoms.
    • Increasing research suggests a potential association between cannabis use and thoughts, perceptions, communications, and behaviors suggestive of schizophrenia, or being prone to psychosis, in the general population.

    The bottom line?

    Dr. Compton concludes, “Ongoing neurobiologic research is revealing findings in the endocannabinoid system that appear to support the biologic plausibility of such links.”

    5/2/10 20:50 JR

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