The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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  • Recent Comments

    Effects of glucosamine + omega-3 on osteoporosis

    Researchers in Germany conducted the first study of this combination.

    The aim was to see if the combination is more effective than glucosamine alone.

    First, the details.

    • 177 patients with moderate-to-severe hip or knee osteoarthritis (OA) were randomly assigned to a treatment for 26 weeks.
      • Group A: Glucosamine sulfate (1500 mg/day) + omega-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)
      • Group B: Glucosamine sulfate alone
    • Neither the patients nor researchers knew the treatment given — double blind.
    • Evaluation was performed using the Western Ontario and McMaster Universities Arthrosis index (WOMAC) score.

    And, the results.

    • Based on the criterion of at least a 20% reduction in the WOMAC pain score there was no difference between treatments (92% Group A, 94% Group B).
    • Based on the criterion of at least an 80% reduction in the WOMAC pain score, glucosamine sulfate + omega-3 was significantly better than glucosamine alone (44% Group A, 32% Group B).
    • OA symptoms of 1) morning stiffness, and 2) pain in hips and knees at the end of the study were 49% vs 56% Group A, respectively; and 42% vs 55% Group B).
    • Both treatments well tolerated over 26 weeks.

    The bottom line?

    There’s support for each component individually. Now there’s support for the combination, which should be followed by more research.

    4/14/10 21:18 JR

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