The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Exclusion diet + nutraceutical therapy to treat juvenile Crohn’s disease

    Encouraging findings in a small group of patients are reported by researchers at Columbia University College of Physicians & Surgeons, in New York.

    First, the details.

    • 6 patients with moderately severe Crohn’s disease participated.
      • 2 had completed growth.
    • All were treated with an exclusion diet with nutraceutical therapy.
    • Adequate caloric and protein intake for catch-up weight was prescribed.
    • Dairy products, certain grains and carrageenan containing foods were eliminated.
      • Carrageenan is a seaweed extract.
    • Nutraceuticals, consisting of fish peptides, bovine colostrum, Boswellia serrata, curcumin, and a multivitamin were taken daily.
    • Lactobacillus GG, a probiotic, was administered twice weekly.
    • Recombinant human GH (rhGH) was administered daily.

    And, the results.

    • Within 2 months of starting the exclusion diet with nutraceutical therapy all 6 patients went into remission and stopped taking all pharmacological drugs.
    • 3 patients have remained in sustained remission for 4 to 8 years.
    • 1 patient with very severe Crohn’s disease had recurrence of symptoms after being in complete remission for 18 months.
    • 1 patient was in remission for 3 years but symptoms recurred when she became less compliant with the exclusion diet with nutraceutical therapy.
    • 1 recently treated patient remains in remission after 6 months.
    • With the addition of rhGH, the 4 growing patients had good-excellent growth response

    The bottom line?

    It’s a very small group of patients.

    The authors believe, “These findings justify larger controlled trials to evaluate the long-term benefit of compliance to exclusion diet with nutraceutical therapy in both juvenile and adult Crohn’s disease patients.”

    More information from 1 of the patients in this study is available here.

    2/13/10 23:05 JR

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