The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at www.Vicus.com, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Treating chronic fatigue syndrome with probiotics

     This study by researchers at the University of Toronto focused on the management of anxiety.

    First, the details.

    • 39 adults with chronic fatigue syndrome were randomly assigned to a treatment for 2 months.
      • 24 billion colony forming units of Lactobacillus casei strain Shirota (LcS) daily
        • or
      • Placebo daily
    • Patients provided stool samples to check for the probiotic.
    • And they completed the Beck Depression and Beck Anxiety Inventories before and after treatment.
    • Neither the patients nor researchers knew the treatment given — double-blind.

    And, the results.

    • There was a significant rise in both Lactobacillus and Bifidobacteria in those taking LcS.
    • There was also a significant decrease in anxiety symptoms among those taking the probiotic vs. controls.

    The bottom line?
    But what’s the connection between changes in intestinal bacterial makeup and improved mental health?

    The authors explain that the idea of implanting the intestines with Lactobacillus strains to improve quality of life and mental health is not a new.

    They review the supporting research and conclude, “The results suggest that specific strains of probiotic bacteria may have a role to play in mediating some of the emotional symptoms of chronic fatigue syndrome and other related conditions.”

    It’s a small study, and the researchers can’t discount “that the decreased anxiety was a consequence of improved bowel function.”

    More research, please.

    4/14/09 1:43 JR

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