The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    If you found the information here helpful, please consider supporting this site.If you found the information here helpful, please consider supporting this site.

  • Recent Posts

  • Recent Comments

    Drug-supplement interactions in perspective

    Researchers from the Mayo Clinic in Rochester, Minnesota have reviewed the evidence and report that most interactions are confined to a relatively small number of drug classes and supplements.

    First, the details.

    • 1818 patients treated at the Mayo Clinic in 6 different specialty clinics were surveyed for their use of dietary supplements.
    • Concurrent use of prescription drugs was obtained from patients’ medical records.
    • A computerized search was used to assess the potential significance of each interaction on the patients’ health.

    And, the results.

    • 710 (40%) of the 1795 patients who responded reported use of dietary supplements.
    • 107 interactions with potential clinical significance were identified.
    • The 5 most common natural products with a potential for interaction accounted for 68% of the potential clinically significant interactions.
      • Garlic
      • Valerian
      • Kava
      • Ginkgo
      • St John’s wort
    • The 4 most common classes of prescription medications with a potential for interaction accounted for 94% of the potential clinically significant interactions.
      • Antithrombotic medications
      • Sedative
      • Antidepressant drugs
      • Antidiabetes drugs

    The bottom line?
    No patient was harmed seriously from any interaction.

    It’s still a good idea to include a list of your supplements with your prescription drugs when you go to the doctor.

    3/22/08 20:31 JR

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