The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    Background on vitamin B-2

    Riboflavin (vitamin B-2) was originally recognized as a growth factor in 1879 and named vitamin B-2 according to the British nomenclature system.

    Here’s what we know today.

    • Riboflavin has two active coenzyme forms.
      • Riboflavin 5′-phosphate (R5P)
      • Flavin adenine dinucleotide (FAD).
    • Dietary sources include milk, eggs, meats, yogurt, broccoli, almonds, cheese, soy, fortified grains, and dark green vegetables, in descending order of concentration.
    • Bacteria in the colon also synthesize riboflavin.
    • Riboflavin or its coenzymes contributes to cellular growth, enzyme function, energy production, and carbohydrate, fat, and amino acid synthesis.

    The bottom line?

    • Research supports the use of riboflavin in…
      • Anemia
      • Cataracts
      • Hyperhomocysteinemia (a condition that damages the blood vessel lining)
      • Migraine prophylaxis
      • Alcoholism
    • A riboflavin deficiency can result in…
      • Angular stomatitis (inflammation at the corner of the mouth)
      • Seborrhea (scaly, flaky, itchy, red skin)
      • Glossitis (swelling and color change of the tongue)
      • Nervous disorders
      • Anemia

    1/21/09 20:26 JR

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