The C.A.M. Report
Complementary and Alternative Medicine: Fair, Balanced, and to the Point
  • About this web log

    This blog is intended as an objective and dispassionate source of information on the latest CAM research. Since my background is in pharmacy and allopathic medicine, I view all CAM as advancing through the development pipeline to eventually become integrated into mainstream medical practice. Some will succeed while others fail. But all are treated fairly here.

  • About the author

    John Russo, Jr., PharmD, is president of The MedCom Resource, Inc. Previously, he was senior vice president of medical communications at, a complementary and alternative medicine website.

  • Common sense considerations

    The material on this weblog is for informational purposes. It is not medical advice or counsel. Be smart, consult your health professional before using CAM.

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    If you found the information here helpful, please consider supporting this site.If you found the information here helpful, please consider supporting this site.

  • Recent Posts

  • Recent Comments

    Saffron to treat PMS

    This is the first study of saffron to treat premenstrual syndrome (PMS) in humans.

    First, the details.

    • Women, 20 to 45 years old, with regular menstrual cycles and PMS for at least 6 months were studied.
    • After monitoring the women for 2 menstrual cycles, they were randomly assigned to take saffron capsules 30 mg/day (15 mg morning and evening) or placebo for an additional 2 menstrual cycles.
    • Neither the researchers nor the women knew the treatment given (blinded).

    And, the results.

    • At the end of the study, 76% of the women taking saffron had a 50% or greater reduction in PMS symptoms, vs 8% of the women taking placebo, a significant difference.
    • There were significant differences between groups in the Hamilton Depression Rating Scale scores — a 21-question multiple choice questionnaire used to rate the severity of a patient’s depression.

    The bottom line?
    It’s a small study, but deserves to be followed-up with another.

    5/8/08 22:10 JR

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